TY  - GEN
AU  - Pieri,Maria
AU  - Pieri,Maria
TI  - The Identification of Drug Abuse
SN  - books978-3-0365-7967-2
PY  - 2023///
CY  - Basel
PB  - MDPI - Multidisciplinary Digital Publishing Institute
KW  - Medicine
KW  - Medical toxicology
KW  - bicssc
KW  - atropine
KW  - scopolamine
KW  - thermal stability
KW  - GC-MS inlet
KW  - degradation
KW  - deep sedation
KW  - drug interaction
KW  - midazolam
KW  - morphine
KW  - palliative care
KW  - terminal patient management
KW  - meconium
KW  - mass spectrometry
KW  - toxicology
KW  - drug of abuse
KW  - orbitrap
KW  - newborn
KW  - diquat
KW  - suicidal ingestion
KW  - patient management
KW  - professional liabilities
KW  - phorate
KW  - pesticides
KW  - carbamazepine
KW  - bipolar
KW  - bone tissue
KW  - blood
KW  - matrix
KW  - concentration
KW  - opioids
KW  - fingernails
KW  - immunohistochemistry
KW  - ultra-high-performance liquid chromatography
KW  - high-resolution mass spectrometry
KW  - forensic toxicology
KW  - unconventional matrices
KW  - helium
KW  - asphyxia
KW  - suicide
KW  - detection and quantification
KW  - acetaminophen
KW  - citalopram
KW  - trazodone
KW  - poly-drug intoxication
KW  - dog attack
KW  - gas chromatography-mass spectrometry
KW  - fentanyl
KW  - transdermal patch
KW  - protective film
KW  - autopsy
KW  - forensic pathology
KW  - intrauterine
KW  - neonatal
KW  - exposure
KW  - medico-legal issues
KW  - Lemborexant
KW  - insomnia
KW  - abuse
KW  - UPLC-MS/MS
KW  - SWGTOX
KW  - DORA
KW  - psychedelics
KW  - LSD
KW  - MDMA
KW  - mescaline
KW  - psilocybin
KW  - lethal dose
KW  - overdose
KW  - n/a
N1  - Open Access
N2  - Over the last decades, interest in forensic toxicology has continually increased. Consequently, the discipline assumed a leading role, becoming one of the reference sciences for elucidating events of judicial importance. The need to reconcile analytical problems (e.g., relating to the qualitative/quantitative analysis of substances of abuse in complex biological matrices) with judicial requirements (i.e., providing data that can be used as documentary evidence in proceedings) makes the discipline unique among all "analytical" sciences. Thus, the availability of validated procedures, the constant monitoring of analytical performance through quality assurance protocols, the availability of certified “in matrix” standards, and the analytical problems underlying the analysis of new psychoactive substances in the blood and other biological fluids represent the challenges of modern forensic toxicology. The correct interpretation of analytical data, especially to elucidate the extent of impairment induced by a certain substance, and “old” issues related to the correct interpretation of post-mortem data (given the impossibility of translating the therapeutic ranges defined in vivo) represent further areas of research and debate among scientists. Finally, the possibility of interacting with other disciplines (such as proteomics and social sciences) allows for extending the concept of analytical data acquisition/interpretation beyond the classical limits of forensic toxicology (for example, considering the influence of gender when interpreting the effect of a substance)
UR  - https://mdpi.com/books/pdfview/book/7494
UR  - https://directory.doabooks.org/handle/20.500.12854/101397
ER  -