The Origin and Early Evolution of Life: Prebiotic Chemistry of Biomolecules

Fiore, Michele

The Origin and Early Evolution of Life: Prebiotic Chemistry of Biomolecules - MDPI - Multidisciplinary Digital Publishing Institute 2019 - 1 electronic resource (288 p.)

Open Access

Studying the origin of life is one of man’s greatest achievements over the last sixty years. The fields of interest encompassed by this quest are multiple and interdisciplinary: chemistry, physics, biology, biochemistry, mathematics, geology but also statistics, atmospheric science, meteorology, oceanography, and astrophysics. Recent scientific discoveries, such as water on Mars and the existence of super-Earths with atmospheres similar to primordial Earth, have pushed researchers to simulate prebiotic conditions in explaining the abiotic formation of molecules essential to life. This collection of articles offers an overview of recent discoveries in the field of prebiotic chemistry of biomolecules, their formation and selection, and the evolution of complex chemical systems.


Creative Commons


English

books978-3-03921-607-9 9783039216062 9783039216079

10.3390/books978-3-03921-607-9 doi

minerals n/a inosine carbamic acid prebiotic chemistry pentopyranose nucleic acid catalysis MVC architecture pattern and biological information carbon dioxide-ammonia ices stability as a selection pressure ribozyme and tRNA translation and the genetic code AnyLogic software for computer simulation of translation machine Darwinian evolution prebiotic information system genetic code origin electrochemistry coevolution of translation machine and the genetic code digit multiplicity thermodynamic bottleneck abasic oligomers selection nucleotide stability AICAR tRNA-synthetase hypercycle nucleotide oligomerization origin of life thioester dry-wet cycles Chemomimesis population growth tRNA and mRNA diversity early peptides Molecular Darwinism tRNA accretion model replication aldol reaction hydrothermal vents base pairing numerical codons abiogenesis purine precursor peptide/RNA world information ab initio molecular dynamics RNA cysteine nucleotide and nucleoside synthesis thiol-rich peptides novel metalloproteins transmission function energy currency anharmonicity arabinopyranose nucleic acid bridge peptide and aaRS aminonitriles mechanochemistry prebiotic polymerization origins of life encoding carbon fixation infrared spectra phosphoryl transfer metabolism growth order layered double hydroxide (LDH) clay molecular clocks Monte Carlo binary patterned amino acid sequences network expansion simulation prebiotic soup nucleotidyltransferases mixed anhydride phosphates translation ribosome pentose diphosphate monosaccharides systems chemistry reduction imidazoles protein design